Understand the value of being a responsible breeder and things to consider before making the commitment.
The AKC provides guidlines spaning the life cycle of breeding, from learning before you begin, preparing to breed, care during the process and the steps involved after birth. They also provide additional resources and information on this topic.
A great compairison list between breeding responsible and being careless.
This website provides information to consider if you're interested in breeding your own dog as well as heriditary and genetic issues to be aware of.